In the part more to the east of the Island, shares with the province of Bayamo the Mestra Mountain range. In his more Eastern part it is the extensive National Park of Baconao, declared Reserve of the Biosphere, and the lagoon of equal name. In the Park you will be able to enjoy its tourist infrastructure, the beaches, the Museum of Mesoamericana Archaeology, the submarine aquarium and a park with gigantic prehistoric animal sculptures. The province is cradle of are and the bolero, as well as of a rich ritual culture of African influence. Their historical coffee plantations franc-Haitians of between centuries XVII and beginnings of the XIX, in the Southeast of the province, were declared Patrimony of the Humanity in November of 2000.

To few kilometers of its capital, Santiago of Cuba, is the sanctuary of the Virgin of the Charity of Cobre, the pattern of Cuba. In addition to agriculture (coffee and cacao), deposits of copper and manganese exist.

Santiago, the second city more populated with the country, was founded by Vela'zquez safe from its bay on 1515. It was residence of the Spanish governor until in the middle of century XVI it was transferred to Havana. Its port was one of the most important points of arrival of the emigrations of the Old Continent. In its bay the Spanish fleet at hands of the North American was defeated in 1898, defeat that marked the exit of Spain of the Island to happen to dominion of the United States. She is famous by the celebration of his Carnival. The neuralgic center of the city is the park Turfs, where it is the Cathedral, the City council and the house of Diego Vela'zquez, also closely together it is the House of the Trova. Other place that you do not have to forget to visit is the Museum Emilio Bacardí or the Moncada quarter, nowadays demilitarized, lodges a museum and a school. To the outskirts it is the Castle of San Pedro of the Rock of the Nose (Patrimony of the Humanity by UNESCO in December of 1997). In the city there is a cafeteria of much enchantment that is called "the Isabelica", is rallying point of all the city.

To few kilometers of the capital, you have magnificent beaches. Towards the east, to about 14 kilometers, you have Siboney, which they follow those of Juraguá, Daikiri, Verraco, Brown Coast, Buccaneer, Sigua and Cazonal to him, while that by the west you have those of Green Sea, Cabón Ox, White Caletón, the French and del municipality of Guamá.